October 23, 2012

university of illinois CANCER CENTER
UPDATE

Becknma


News briefs


Did you know that the upcoming month of November is Movember? Movember is the nationally-driven, month-long awareness campaign and funding initiative for prostate and testicular cancers.  Beginning November 1, clean-shaven men honor the millions of men that fight the prostate and/or testicular cancer battle, by growing a month-long mustache.  With the often-minimized attention given to men’s health issues, Movember provides 30 days of opportunity to raise awareness of men’s cancers and funding to find a cure.  Additional information about Movember can be found at the following link: http://us.movember.com/?home.

Mustache__________________________________________________________________________

CONGRATULATIONS to the University of Illinois Cancer Program, which recently received an Accreditation Award for three years, with Commendation by the American College of Surgeons’ Commission on Cancer (COC)!  This accreditation honors not only the scientific talent and wealth of research that is developed and presented by the University of Illinois, but also recognizes the value that the University of Illinois  Cancer Center places on their patients, patient outcomes and community resources to address cancer disparities.  This Accreditation Award further exemplifies the University of Illinois’ commitment to building a foundation of cancer research and patient care in the Illinois medical arena.

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CONGRATULATIONS to Dr. Xavier Llor, who received a Proof of Concept Gap Funding Initiative, offered through the UIC Office of Technology Management (OTM).  The Proof of Concept Gap Funding Initiative was developed for researchers with a technology disclosure, to overcome the hurdle of making discoveries in scientific research and transitioning those discoveries into marketable products.  The OTM recognizes that science and the research needed to advance science, can only exist with sufficient funding.  Dr. Llor’s research is in the development of a non-invasive test of colon cancer screening.  As colon cancer is the third most common cause of cancer-related death in the U.S., the most current and most accurate screening technique is the colonoscopy.  However, the challenging preparation necessary for a colonoscopy means that many patients either cannot complete the necessary pre-testing instructions or are too fearful of the test to have it done. Likewise, the colonoscopy procedure itself has some risks.  Llor’s research, in tandem with associate Rosa Xicola, explores blood samples that can detect the presence of early colon cancer or even advanced polyps within circulating microRNA levels, found in plasma.  With early success, Llor is hoping that a simple blood test can not only minimize the colonoscopy screening process, but also dramatically increase screening rates, therefore saving lives .

Dr. Xavier Llor

Additional related Proof of Concept Gap Funding Initiatives were awarded to Dr. Hayat Onyuksel and Dr. Samuel Dudley, and their respective research teams.  Dr. Onyuksel’s research is within gene therapy, with the intent to target liver disease.  Her hope is that gene therapy can target specific cells within the body, without affecting healthy genes.  She also foresees that success with this could carry over to treat various cancers and heart disease.  Dr. Dudley’s research is in the development of a blood test that could indicate specific types of heart failure.  With clinical trials current in-progress, Dudley sees this test as both a diagnostic and treatment tool.  Congratulations to both Dr. Onyuksel and Dr. Dudley!  

 

Dr. Samuel Dudley Dr. Onyksel

 

Coming soon on the University of Illinois Cancer Center website – the Diet and Behavior Shared Resource (DBSR) links!  Launching on November 1, 2012, the DBSR invites you to connect with their services and explore the various assessment tools and research within diet, fitness, physical activity, body composition/anthropometrics, tobacco use and lifestyle, and how those factors may relate to cancer and specific populations affected by cancer. The new DBSR links will be emailed to all Cancer Center members and affiliated personnel, and links will be provided on the Cancer Center home page!

It was a packed house at the October 18, 2012 Cancer Center Planning Meeting, held at the Beckman Institute in Urbana, IL.  In attendance were Cancer Center members, program leaders, undergraduates, grad students and those interested in cancer and the limitless potential that the University of Illinois Cancer Center offers to the cancer community.  The day was focused on the institution’s dedication to the science of cancer, as well as building the comprehensive collaboration between Colleges within the University of Illinois, and across disciplines.  In addition to addressing cancer disparities and seeking the best options for underserved populations, the UI Health system is moving forward in addressing all manners in which cancer expresses itself, from its molecular, cellular and genetic components, to its behavioral effects on various populations and obstacles to prevention.  Special thanks to Dr. Rohit Bhargava, Dr. Margaret Browne-Huntt, and Gretchen Clifton, for coordinating this event!

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NEW FUNDING OPPORTUNITIES:

AACR Cancer Development Awards
Sponsor: Pancreatic Cancer Action Network, AACR

Deadline:  App 10/31/2012

Encouragement and support for junior faculty who are in the first five years of a faculty appointment (at the start of the grant term) to conduct pancreatic cancer research and establish successful career paths in this field.  The research proposed for funding may be basic, translational, clinical or epidemiological in nature and must have direct applicability and relevance to pancreatic cancer.

 

AACR-Aflac Incorporated Career Development Award for Pediatric Cancer Research
Sponsor:  AACR, Aflac, Inc.

Deadline:  App 11/12/2012

Encouragement and support for junior faculty who are in the first five years of a faculty appointment (at the start of the grant term) to conduct pediatric cancer research and establish successful career paths in this field.  The research proposed for funding may be basic, translational, clinical or epidemiological in nature and must have direct applicability and relevance to pediatric cancer.

 

AACR – National Brain Tumor Society Career Development Award for Translational Brain Tumor Research
Sponsor:  AACR, National Brain Tumor Society

Deadline:  App 11/12/2012

Encouragement and support for junior faculty who are in the first five years of a faculty appointment (at the start of the grant term) to conduct brain tumor research and establish successful career paths in this field.  The research proposed for funding must be translational in nature and have direct applicability and relevance to brain tumors.

 

AACR Dharma Master Jiantai Innovative Grant for Lung Cancer Research
Sponsor: AACR, Dharma Master Jiantai

Deadline: App 11/20/2012

Funding granted to an investigator for an existing project that develops and studies new ideas and approaches that have direct application and relevance to lung cancer.  Following the Grant-in-Aid of Research model, this support supplements existing funding for an investigator conducting a basic or translational research project that will contribute to the acceleration of progress against lung cancer, for the ultimate goal of improving patient care.

 

Advanced Development of Informatics Technology (U24)
Sponsor: NIH, NCI

Deadline: Earliest submission – 1/22/2013

Purpose is to invite Cooperative Agreement (U24) applications for advanced development and enhancement of emerging informatics technologies to improve the acquisition, management, analysis, and dissemination of data and knowledge in cancer research. An emerging informatics technology is defined as one that has passed the initial prototyping and pilot development stage, has demonstrated potential to have a significant and broader impact, has compelling reasons for further improvement and enhancement, and has not been widely adopted in the cancer research field. If successful, these technologies would accelerate research in cancer biology, cancer treatment and diagnosis, cancer prevention, cancer control and epidemiology, and/or cancer health disparities. This FOA is one component of the NCI's Informatics Technology for Cancer Research (ITCR) Initiative whose central mission is to promote research-driven informatics technology development.  Potential applicants who are interested in early-stage development should consult companion FOAs listed on the previous page.  Applications that focus on informatics data processing and analysis or mathematical/statistical modeling alone without informatics technology development are not appropriate for this FOA.

 

Early-Stage Development of Informatics Technology (U01)
Sponsors: NIH, NCI

Deadline: Earliest submission 12/22/2012

Purpose is to invite Cooperative Agreement (U01) applications for the development of enabling informatics technologies to improve the acquisition, management, analysis, and dissemination of data and knowledge in cancer research. As a component of the NCI's Informatics Technology for Cancer Research (ITCR) Initiative, this FOA focuses on early-stage development from prototyping to hardening and adaptation. The central mission of the ITCR is to promote research-driven informatics technology development. In order to be successful, proposed development plans must have a clear rationale on why the proposed technology is needed and how it will benefit the cancer research community. In addition, mechanisms to solicit feedback from users and collaborators throughout the development process should be included. Applications that focus on data processing and analysis or mathematical/statistical modeling alone without new technology development are not appropriate for this FOA.

 

Exploratory/Developmental Bioengineering Research Grants (EBRG) (R21)
Sponsors: NIH; NCI; National Institute of Biomedical Imaging and Bioengineering; National Heart, Lung and Blood Institute; National Institute on Alcohol Abuse and Alcoholism; National Institute of Arthritis and Musculoskeletal and Skin Diseases; Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institute of Dental and Craniofacial Research; National Institute on Drug Abuse; National Institute of Environmental Health Sciences; National Institute of Neurological Disorders and Stroke; Office of Research on Women’s Health

Deadline: 1/16/2013

Purpose is to establish the feasibility of technologies, techniques or methods that: 1) explore a unique multidisciplinary approach to a biomedical challenge; 2) are high-risk but have a considerable pay-off; and 3) develop data which can lead to significant future research. An EBRG application may propose hypothesis-driven, discovery-driven, developmental, or design-directed research and is appropriate for evaluating unproven approaches for which there is minimal or no preliminary data.

 

Effects of In Utero Alcohol Exposure on Adult Health and Disease (R01)
Sponsor: NIU, National Institute on Alcohol Abuse and Alcoholism (NIAAA)

Deadline:  Earliest submission – 1/5/2013

Intended for support of novel research on how prenatal alcohol exposure may contribute to the tiology of chronic diseases and health conditions later in life.  Central to this theme is the developmental origins of health and disease (DOHaD) concept, which suggests that fetal adaptations in response to adverse intrauterine conditions may increase the risk for childhood and adult disease.  The foald of this FOA is to stimulate a broad range of research to: 1)leverage existing prospective birth cohorts to define the role fo maternal alcohol consumption in the DOHaD process; 2) investigate the biological, cellular and molecular mechanisms by which prenatal alcohol exposure may impact disease outcomes later in life; and 3) identify biomarkers associated with gestational alcohol exposure that may predict adult disease susceptibility in exposed offspring.  Studies supported by this FOA will provide fundamental insights into a possible fetal-basis to adult disease that is influenced by maternal alcohol use.

 

Effects of In Utero Alcohol Exposure on Adult Health and Disease (R21)
Sponsor: NIU, National Institute on Alcohol Abuse and Alcoholism (NIAAA)

Deadline:  Earliest submission – 1/16/2013

Intended for support of novel research on how prenatal alcohol exposure may contribute to the tiology of chronic diseases and health conditions later in life.  Central to this theme is the developmental origins of health and disease (DOHaD) concept, which suggests that fetal adaptations in response to adverse intrauterine conditions may increase the risk for childhood and adult disease.  The foald of this FOA is to stimulate a broad range of research to: 1)leverage existing prospective birth cohorts to define the role fo maternal alcohol consumption in the DOHaD process; 2) investigate the biological, cellular and molecular mechanisms by which prenatal alcohol exposure may impact disease outcomes later in life; and 3) identify biomarkers associated with gestational alcohol exposure that may predict adult disease susceptibility in exposed offspring.  Studies supported by this FOA will provide fundamental insights into a possible fetal-basis to adult disease that is influenced by maternal alcohol use.

 

Examination of Survivorship Care Planning Efficacy and Impact (R21)
Sponsors: NIH, NCI

Deadline:  Earliest submission – 1/5/2013

Purpose is to stimulate research to evaluate the effect of care planning on cancer survivors' health and psychosocial outcomes; self-management of late effects and adherence to cancer screening and health behavior guidelines; utilization of follow-up care; organizational-level factors influencing the implementation of care planning; and associated costs. Specifically, the FOA aims to stimulate research that will: 1) develop and test metrics for evaluating the impact of survivorship care planning; 2) evaluate the impact of survivorship care planning on cancer survivors' morbidity, self-management and adherence to care recommendations, utilization of follow-up care, and on systems outcomes, such as associated costs and impact on organizations implementing care planning; and 3) identify models and processes of care that promote effective survivorship care planning. The ultimate goal of this FOA is to generate a body of science that will inform the development and delivery of interventions and best practices in follow-up care for cancer survivors. 

 

Examination of Survivorship Care Planning Efficacy and Impact (R01)
Sponsors: NIH, NCI

Deadline:  Earliest submission – 1/5/2013

Purpose is to stimulate research to evaluate the effect of care planning on cancer survivors' health and psychosocial outcomes; self-management of late effects and adherence to cancer screening and health behavior guidelines; utilization of follow-up care; organizational-level factors influencing the implementation of care planning; and associated costs. Specifically, the FOA aims to stimulate research that will: 1) develop and test metrics for evaluating the impact of survivorship care planning; 2) evaluate the impact of survivorship care planning on cancer survivors' morbidity, self-management and adherence to care recommendations, utilization of follow-up care, and on systems outcomes, such as associated costs and impact on organizations implementing care planning; and 3) identify models and processes of care that promote effective survivorship care planning. The ultimate goal of this FOA is to generate a body of science that will inform the development and delivery of interventions and best practices in follow-up care for cancer survivors.

 

Landon Foundation – AACR INNOVATOR Award for Cancer Prevention Research
Sponsor: Landon Foundation, AACR

Deadline:  App 11/20

The Landon Foundation – AACR INNOVATOR Award for Cancer Prevention Research was established to recognize the outstanding achievement of a junior faculty-level scientist working in the field of cancer prevention, and support his or her novel and innovative research that, if successful, will have strong potential for high impact in the cancer prevention field.

 

Pancreatic Cancer Action Network – AACR Fellowship
Sponsor: Pancreatic Cancer Action Network, AACR

Deadline: App 10/31/2012

Encouragement and support for a post-doctoral or clinical research fellow who is in the first three years of his/her fellowship training (at the start of the grant term) to conduct pancreatic cancer research and establish a successful career path in this field.  The research proposed for funding may be basic, translational, clinical or epidemiological in nature and must have direct applicability and relevance to pancreatic cancer.

 

Revisions for Early-Stage Development of Informatics Technology (R01)
Sponsor: NIH, NCI

Deadline: Earliest submission – 12/22/1012

Purpose is to is to encourage revision applications (formerly called "competing revisions") from currently funded NCI R01 and R37 (MERIT) research projects for early-stage development of enabling informatics technologies to improve the acquisition, management, analysis, and dissemination of data and knowledge. As a component of the NCI's Informatics Technology for Cancer Research (ITCR) Initiative, this FOA aims to promote interdisciplinary collaboration in the development of innovative computational methods and informatics approaches that are essential for cancer research on all fronts to accelerate scientific discovery and ultimately translate data into knowledge and clinical practice. Applications that focus on data processing and analysis or mathematical/statistical modeling alone without new technology development are not appropriate for this FOA.

Revisions for Early-Stage Development of Informatics Technology (U01)
Sponsors: NIH, NCI

Deadline: Earlist submission 12/22/2012

Purpose is to invite revisions (formerly called "competing revisions") from currently funded NCI U01 cooperative agreement projects for early-stage development of enabling informatics technologies to improve the acquisition, management, analysis, and dissemination of data and knowledge. As a component of the NCI's Informatics Technology for Cancer Research (ITCR) Initiative, this FOA aims to promote interdisciplinary collaboration in the development of innovative computational methods and informatics approaches that are essential for cancer research on all fronts to accelerate scientific discovery and ultimately translate data into knowledge and clinical practice. Applications that focus on data processing and analysis or mathematical/statistical modeling alone without new technology development are not appropriate for this FOA.

 

Revisions for Early-Stage Development of Informatics Technology (P01)
Sponsors: NIH, NCI

Deadline: Earliest submission 1/22/2013

Purpose is to invite revisions (formerly called "competing revisions") from currently funded NCI P01 program projects for early-stage development of enabling informatics technologies to improve the acquisition, management, analysis, and dissemination of data and knowledge. As a component of the NCI's Informatics Technology for Cancer Research (ITCR) Initiative, this FOA aims to promote interdisciplinary collaboration in the development of innovative computational methods and informatics approaches that are essential for cancer research on all fronts to accelerate scientific discovery and ultimately translate data into knowledge and clinical practice. Applications that focus on data processing and analysis or mathematical/statistical modeling alone without new technology development are not appropriate for this FOA. 

 

Specialized Programs of Research Excellence (SPORESs) in Human Cancer for Years 2012 and 2014 (P50)
Sponsors: NIH, NCI, National Institute of Dental and Craniofacial Research (NIDCR)
National Institute of Neurological Disorders and Stroke (NINDS)

Deadline:   1/24/2013; 9/3/2014

Program will fund 5-year P50 SPORE grants to support state-of-the-art investigator-initiated translational research that will contribute to improved prevention, early detection, diagnosis, and treatment of an organ-specific cancer (or a related group of cancers).  SPOREs are expected not only to conduct a wide spectrum of research activities, but also to contribute significantly to the development of specialized shared resource core facilities (cores), improved research model systems, and collaborative research projects with other institutions. The research supported through this program must be translational in nature and must always be focused upon knowledge of human biology stemming from research using cellular, molecular, structural, biochemical, and/or genetic experimental approaches with the goal of a translational human endpoint within the 5 year term of the grant. In addition, SPOREs must include both a Developmental Research Program for pilot studies and a Career Development Program to foster careers in organ-based translational science.

 



 

 


In this issue

 

upcoming events

 

Recent Publications

  funding opportunities

 

 


Click here for new
Funding Opportunities.

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UPCOMING CANCER CENTER EVENTS

Robert H. Costa 6th Annual Symposium:

Sexual Dimorphism of Liver Cancer -

It All Depends on FoxA

October 24, 2012; 11:40 AM - 1:00 PM

MBRB Herman Auditorium

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Center for Pharmaceutical Biotechnology Presents: Using P. aeruginosa to Unravel Apoptotic Compensatory Proliferation Signaling: Implication on Cancer Biology and Therapy

        October 25, 2012; 12:00 PM

in the 3rd FL Library, MBRB

_______________________________ Town Hall Forum:

How to Beat Breast Cancer-

What Every Woman Should Know!

**Registration required

October 25, 2012; 11:00 AM – 3:00 PM

New Zion Missionary Church Banquet Center, 1940 W. 13th St., Chicago

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Breast Cancer Awareness Match Featuring the Chicago Fire Major League Soccer Team vs. DC United

        October 27, 2012; 3:00 PM, at

Toyota Park, Home of the Chicago Fire

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Biomedical and Health Informatics Colloquium Second Seminar of 2012:

Informatics Tools to Facilitate Evidence-Based Medicine

        October 29, 2012; 12:00 – 1:00 PM

COMRB, Rm 5175

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Town Hall Meeting - Multidisciplinary Management of Colorectal Cancer (CRC): A Community Perspective

October 30, 2012; 6:30 pm - 9:00 pm

Hotel Intercontinental, Chicago

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7th Annual Dr. Antonio Scommegna Symposium and the 12th Annual Dr. Laird Wilson Jr. Perinatal Symposium: Confronting Issues in Obstetrics

                November 2-3, 2012; time TBA

Student Center West

2nd Fl Conference Rm

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Advances in Myeloproliferative Neoplasms

November 16, 2012; 2:00 -6:00 pm

COMRB, Moss Auditorium

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Bridging the Gap: Emerging Health Issues in Underrepresented Minorities

    November 17, 2012;  8:30 AM – 3:00 PM

UIC Forum

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RECENT PUBLICATIONS

A High-Throughput Assay to Identify Small-Molecule Modulators of Alternative Pre-mRNA Splicing
            Beck, WT, et al.

Infrared Spectroscopic Imaging: The Next Generation
            Bhargava, R

Looking in the Mouth for Noninvasive Gene Expression-based Methods to Detect Oral, Oropharyngeal, and Systemic Cancer.
            Adami, GR, et al.
 

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