Still More Fellowships

October 27, 2013

Sabine Kreilinger MD, our current Neuroanesthesia fellow, will be starting a Critical Care Medicine fellowship at Northwestern for the 2014-2015 academic year. Congratulations Sabine!

More Fellowships

October 27, 2013

Lisa Adiutori, MD and Desiree Ekundayo, MD, current CA-3 residents, will be staying on as Neuroanesthesia fellows here at the University of Illinois for the 2014-2015 academic year. Congratulations to both of them!

Highlights From ASA Annual Meeting

October 24, 2013

Dr. Erick Isaacson

Dr. Fathi Kolonda

Dr. Jennifer Mendoza

Dr. Karmin Nissan

Dr. Christina Smith

Grant will fund development of chemical countermeasures

Sharon Parmet

October 21, 2013

An interdisciplinary group of researchers at the University of Illinois at Chicago will investigate whether a therapy currently used to treat certain drug overdoses may be protective in the event of a chemical attack. The research will be supported by a five-year, $3.5 million CounterACT grant from the National Institutes of Health.

L to R, Dr. Guy Weinberg, Dr. Doug Feinstein, Dr. Israel Rubinstein

Guy Weinberg, professor of anesthesiology,Doug Feinstein, research professor of anesthesiology, and Rudi Rubinstein, professor of medicine, all in the UIC College of Medicine. Photo: Joshua Clark

Principal investigator on the grant is Douglas Feinstein, research professor of anesthesiology in the UIC College of Medicine. He and colleagues in the UIC colleges of Medicine, Engineering, and Pharmacy will study the efficacy of a high-fat liquid called a lipid emulsion for treating sudden exposure to fat-soluble compounds that could be used as chemical weapons.

The lipid emulsion they will study is already approved by the FDA as a nutritional supplement.  It has also been used off-label to treat overdoses of fat-soluble drugs including anesthetics, beta blockers, calcium-channel blockers and certain antidepressants. The UIC researchers believe that the lipid emulsion may be effective against agents with potential for being weaponized, including a widely used rodenticide. They will also investigate whether lipid emulsion can prevent long-term neurological damage from chemical agents.

“Right now, lipid emulsion is given intravenously, but starting IVs and setting up to administer infusions  for large numbers of people in an emergency scenario is impractical,” said Dr. Israel Rubinstein, professor of medicine in the UIC College of Medicine and a co-primary investigator on the grant.

The researchers are looking at delivering lipid emulsion as an injection into the bone marrow, which has a rich blood supply and should allow the emulsion to diffuse rapidly throughout the body.

“First responders can give shots of lipid emulsion to large numbers of people very quickly using a specialized injection device that looks a bit like a gun that can poke right through clothing,” said Feinstein.

“We are hoping that this grant is just the first step in establishing a chemical-countermeasures center here at UIC,” he said.

Dr. Guy Weinberg, professor of anesthesiology in the UIC College of Medicine and the discoverer of lipid-emulsion treatment for drug toxicity, is a co-primary investigator on the grant. He is also a staff physician at the Jesse Brown VA Medical Center, where Dr. Rubinstein is a staff physician and associate chief of staff. Dale Pelligrino, professor of anesthesiology in the UIC College of Medicine; Belinda Akpa, assistant professor of chemical engineering in the UIC College of Engineering; and Richard Van Breemen, professor of medicinal chemistry in the UIC College of Pharmacy; are also investigators on the grant.

The research is supported by NIH CounterACT grant 1U01NS083457-01.

Announcing Fellowships, Here And Elsewhere

October 11, 2013

More of our current senior residents have secured fellowships for the 2014-2015 academic year. Patricia Jumelle, MD has accepted a Pain Medicine fellowship at the University of Washington. Niekoo Abbasian, MD andDiana Ruehlmann, MD will be starting pediatric anesthesia fellowships at the Cincinnati Children’s Hospital. Mark Farag, MD, Anil Ladhani, MD, and Adrian Pichurko, MD will be staying with us as Pain Medicine fellows next year. Congratulations to each of them!