BMS 668 Medical Genetics: 2 Credit Hours
Placement in the Curriculum: Year One
Synopsis: Life as we know it exists because of the gene. Medical Genetics teaches students the basis for gene action in creating normal phenotypes and disease phenotypes. These concepts are taught in the context of mechanisms of mutagenesis, modes of inheritance, gene action, molecular genetics and molecular technology. Medical Genetics builds on the knowledge base acquired in Medical Biochemistry.
Competencies: In the process of completing this course, students acquire the following competencies:
● Understanding of the mechanisms of mutagenesis and the molecular technology that has been developed to detect
● Understanding of the various modes of genetic transmission and their impact on the occurrence of disease
● Understanding of the developments in molecular technology that allows elucidation of the molecular basis of disease and provides for improved medical intervention.recurrence risks, and linkage analysis with marker polymorphisms.
Key Words: Mutagenesis, molecular genetics, recessive genetic transmission, dominant genetic transmission, chromosomal abnormalities, multifactorial inheritance, mitochondrial inheritance, cancer genetics, developmental genetics, population genetics, the human genome.
Assessment: A midterm and a final exam.
Instructional Features: Lectures, study questions, review sessions.